Course Information
Course title
Special Topics in Pharmacology 
Semester
103-1 
Designated for
COLLEGE OF MEDICINE  GRADUATE INSTITUTE OF PHARMACOLOGY  
Instructor
CHING CHOW CHEN 
Curriculum Number
Phmco7019 
Curriculum Identity Number
443 M1280 
Class
 
Credits
Full/Half
Yr.
Half 
Required/
Elective
Required 
Time
Tuesday 2,3,4(9:10~12:10) 
Remarks
The upper limit of the number of students: 30. 
Ceiba Web Server
http://ceiba.ntu.edu.tw/1031Phmco7019_ 
Course introduction video
 
Table of Core Capabilities and Curriculum Planning
Table of Core Capabilities and Curriculum Planning
Course Syllabus
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Course Description

THE MAIN OBJECTIE OF THIS COURSE IS TO TEACH GRADUATE STUDENTS THE MOLECULAR MECHANISMS OF DRUG ACTIONS AND THEIR APPLICATIONS IN PHARMACOLOGICAL RESEARCH TO ENABLE THE STUDENTS TO STUDY EFFECTS OF DRUGS CURRENTLY USED AND NEWLY DISCOVERED BOTH IN VITRO AND IN VIVO.
PHARMACODYNAMICS DEALS WITH THE PRINCIPLES OF DRUG EFFECTS IN THE CELL AND IN THE BODY WITH AN EMPHASIS AT THE MOLECULAR LEVEL. THE COURSE ALSO COVERS FUNDAMENTAL CONCEPTS OF PHARMACOGENETICS AND PHARMACOKINETICS, INCLUDING DRUG EFFECTS ON NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, ENDOCRINE SYSTEM, RESPIRATORY SYSTEM AND GASTROINTESTINAL SYSTEM, IMMUNE SYSTEM AS WELL AS CHEMOTHERAPEUTIC AGENTS, ANTI-COAGULANTS AND ANTI-INFLAMMATORY DRUGS. THE UP-TO-DATE KNOWLEDGE AND DEVELOPMENT IN PHARMACOLOGY WILL BE INCLUDED FROM TIME TO TIME TO BROADEN THE STUDENTS’ VIEW ABOUT SCIENCE.
THE SCORES OF STUDENTS ARE BASED ON THE MID-TERM AND FINAL EXAMINATIONS.
 

Course Objective
 
Course Requirement
 
Student Workload (expected study time outside of class per week)
 
Office Hours
 
Designated reading
 
References
 
Grading
   
Progress
Week
Date
Topic
第2週
9/23  General Signalings 
第3週
9/30  NF-κB 
第4週
10/07  Histone modification 
第6週
10/21  ER Stress Response  
第8週
11/04  Excitation-contraction coupling in heart 
第9週
11/11  Basic electrophysiological techniques 
第10週
11/18  Electrophysiological studies in the heart 
第11週
11/25  Electrophysiological studies in the CNS (1)— Preparations  
第12週
12/02  Electrophysiological studies in the CNS (2)— Methods 
第13週
12/09  Electrophysiological studies in the CNS (3)— Applications 
第14週
12/16  Ca2+ signaling  
第15週
12/23  Cell migration, angiogenesis and cancer metastasis 
第16週
12/30  Systemic and quantitative biomedical research